Pofunitsitsa kukwaniritsa cholinga chawo, anthu ambiri amatha kugwiritsa ntchito zinthu zowoneka bwino kwambiri, ndipo nthawi zambiri, omwe kugwiritsa ntchito kwawo mankhwala sikugwirizana ndi zomanga thupi, zikuwoneka, monga momwe ziliri ndi zomwe tikambirane mu izi nkhani: Dinoprost Tromethamine (Lutalysis).
Inde, izi ndizofala kwambiri! Tsiku lililonse timawona anthu ochulukirapo akugwiritsa ntchito zinthu zosiyanasiyana, osadziwa ngakhale komwe adachokera, kapena cholinga chawo.
Mwanjira imeneyi, amatha kuyamba kuthamangitsidwa pogwiritsa ntchito chilichonse chomwe akuganiza kuti ndichabwino ndipo saganiziranso zofufuza. ndichiyani, kapangidwe kake, Zotsatira zoyipa etc… Zonsezi, chifukwa amafuna thupi langwiro mu nthawi yochepa.
Munkhaniyi, tikambirana za chinthu chovuta kwambiri komanso chosiyanitsa: a Dinoprost tromethamine. Tiyeni timvetsetse kuti ndi chiyani, ndi chiyani, zotsatira zake zoyipa komanso momwe tingazigwiritsire ntchito (kwa olimba mtima kwambiri).
Nazi?
Ndi chiyani?
A Dinoprost tromethmine ndi njira yopangira mankhwala ya malowa achilengedwe Khalani. Prostaglandins ndi mafuta angapo osakwaniritsidwa, okosijeni, ozungulira omwe amakhala ndi machitidwe osiyanasiyana amthupi mthupi.
Mwazina, Alpha ya PGF2 imakhudzidwa ndi vasoconstriction, kuchuluka mapuloteni kaphatikizidwe ayi minofu ya mnofu Chigoba minofu ndi kuchepetsa adipose minofu misa.
Mankhwalawa amalimbikitsanso kutsekemera kwa minyewa yosalala ndipo amakhudzidwa ndi ululu, kutupa, malungo, ovulation, chapamimba motility komanso kuyamwa kwamadzimadzi m'mimba.
Mu zamankhwala zanyama, dinoprost mankhwala imagwiritsidwa ntchito kwambiri nthawi yobereka / kulunzanitsa, kuchiza matenda osachiritsika monga endometriosis, ndikupangitsa kuperewera padera kapena kubereka.
Dinoprost siyigwiritsidwe ntchito kwambiri ngati mankhwala amunthu, koma nthawi zina imagwiritsidwa ntchito kuthetsa mimba kapena kuyambitsa ntchito.
Ochita masewera olimbitsa thupi amakonza dinoprost mankhwala chifukwa cha thermogenesis yake yolimba komanso zotsatira zake anabolic, yomwe yawunikidwa ndi maphunziro a zachipatala, omwe asonyeza kuti PGF2a ndi stimulator yamphamvu ya kaphatikizidwe ka mapuloteni, komanso chinsinsi cha kusintha kwadzidzidzi komanso kwa nthawi yaitali kwa thupi mu maphunziro otsutsa.
Othamanga omwe ayesa wothandizira uyu, nthawi zambiri, amachirikiza lingaliro lakuti gululi ndilolimbikitsa kwambiri kukula kwa minofu zokhazikika, zomwe nthawi zambiri zimayambitsa kukula kwa minofu ndi tanthauzo.
Ananenanso kuti dinoprost Ndi mankhwala ogwiritsira ntchito mwachangu kwambiri, ambiri amati zotsatira zake ndi zabwino atalandiridwa m'gulu linalake laminyewa kwa milungu ingapo.
Deta imathandizanso kuti ndi mankhwala amphamvu kutaya mafuta chachikulu, ndi maphunziro omwe PGF2a amalepheretsa kukondoweza kwa lipogenesis m'maselo amafuta.
Pali malipoti omwe amatsimikizira izi Dinoprost tromethamine pakati pa othamanga ndi omanga thupi, ambiri akunena kuti amawona kutentha pang'ono ndi kutayika kwamafuta panthawi yamankhwala.
Ndi chiyani?
O Dinoprost tromethamine idayambitsidwa koyamba m'makliniki kumayambiriro kwa zaka za m'ma 1970. Kugwiritsa ntchito koyamba kwa mankhwalawa kwa odwala mwaumunthu ndikulimbikitsa kuchotsa pakati pa trimester yachiwiri yapakati.
Kugwiritsiridwa ntchito kwake pazifukwa izi kwakhalabe, koma kumagwirizanitsidwa kwambiri ndi mankhwala a Chowona Zanyama. Apa, imagwiritsidwa ntchito kwambiri kuthandiza olima kuwongolera kuzungulira ndi kubala kwa ziweto. Pali chidwi chachikulu Dinoprost tromethamine monga mankhwala a anabolic ndi thermogenic kwa othamanga komanso omanga thupi pambuyo pa ma 1990.
Izi mwina zidatsatira kutulutsidwa kwa maphunziro angapo azachipatala olumikiza PGF2 alpha ndi matenda oopsa mwamisempha.
Malingaliro omwe abwera kuchokera ku kafukufukuyu asintha kukhala machitidwe amakono ogwiritsa ntchito mankhwalawa, koma ngakhale zili choncho pali kuthekera kopanga zotsatira zoyipa mwa othamanga ambiri komanso omanga thupi.
Kwa zaka zambiri, Dinoprost tromethamine awonekera m'mashelufu azamankhwala amunthu pansi pa mayina ambiri amalonda, kuphatikiza mankhwala odziwika bwino monga Amoglandin (Sweden), Prostin (Sweden), Prostin F2 alpha (US, Australia, Israel, Italy, New Zealand, South Africa ndi United Kingdom ), Minprostin F2a (Germany), Enzaprost (Greece, Poland) ndi Prostarmon (Japan). Prostin F2 sigulitsidwanso ku US, komabe, pakadali pano palibe njira yovomerezeka yogwiritsira ntchito anthu.
Mitundu ya ziweto ilipo ndipo imakonda kupereka mankhwala ochepetsa ndalama zochepa kuposa momwe amathandizira anthu.
Mitundu yotchuka ya ziweto ndi Lutalyse (Pharmacia Animal Health), Prostamate (Pfizer), Panacelan (Daiichi Pharmaceutical Co) ndi Dinolytic (Upjohn).
Kuphatikizana kwamakampani angapo kwachitika mgawo ili la msika ndipo (tsopano wokulirapo) conglomerate Pharmacia yakhala mtsogoleri wazogulitsa dinoprost. Kulimbana mawonekedwe omwe amagwiritsidwa ntchito kwambiri a Dinoprost tromethamine pakati pa akatswiri othamanga / omanga thupi.
dinoprost tromethamine Amakonda kupezeka mu botolo la mankhwala angapo (5 mL-100 mL) pamlingo wa 5 mg pa mL. Amakonzedwa ndi madzi osakaniza ndi benzyl mowa, sodium hydroxide ndi / kapena hydrochloric acid yowonjezedwa ngati njira yothetsera pH.
Zotsatira zoyipa ndi zotsutsana:
Zotsatira zoyipa zitha kuphatikizira zotsatira za kupuma monga:
- Kusokonekera kwa broncho;
- kupuma;
- Chifuwa;
- Kukwiya m'mapapo mwanga;
- Kupuma mofulumira; ndipo
- Anaphylaxis.
Anthu achifuwa amatha kukhala pachiwopsezo cha izi. dinoprost ingayambitsenso kusokonezeka m'mimba, monga: kupweteka kwa m'mimba, kutsegula m'mimba, kusanza ndi mseru. Zotsatira zina zingaphatikizepo: kuchuluka kwa kugunda kwa mtima, kuthamanga kwa magazi, kuzizira, malungo ndi anorexia.
Kwa akazi: Kutsekula kwa chiberekero, kutuluka magazi kumaliseche ndi chiberekero kapena matenda amikodzo. monga amayi apakati sayenera kumwa dinoprost, popeza chiopsezo chopita padera ndi chachikulu kwambiri.
Malipoti a zotsatirapo pakati pa othamanga ntchito dinoprost kusintha thupi kapena ntchito ndizofala ndipo nthawi zambiri zimakhala zovuta. Izi zimaphatikizapo kuwonongeka kodziwika pamalo opangira jakisoni, nthawi zambiri kumayamba ndi kumva kuyaka ndi kuluma pafupifupi nthawi yomweyo jekeseni.
Kuzizira komanso kumva ngati chimfine kumafotokozedwanso pafupipafupi, monganso nthawi yopumira.
Majekeseni amatsatiridwanso ndi chilakolako chosalamulirika chofuna kukodza kapena kuchita chimbudzi, kuphatikizapo kukodza kwambiri. spasmodic ya minofu okhudzidwa ndi kuyang'anira ntchitozi. Mseru ndi kusanza zinanenedwanso mofala.
Kwa ambiri, kukokana, kutsegula m'mimba, kupweteka komanso kumva kuwawa m'mimba, kufooka komanso kusowa mtendere kumapangitsa dinoprost kukhala mankhwala otetezedwa. Ena, amapitilizabe ndi mankhwalawa ndipo, nthawi zambiri, mbali yosavutayi ya zotsatirapo zake imatha kupiririka pakapita nthawi.
Ponena za kugwiritsidwa ntchito ...
Monga mankhwala amunthu, Dinoprost tromethamine Nthawi zambiri amapatsidwa intra-amniotically pamlingo wa 40 mg kuti athetse mimba. Nthawi zina amaperekanso pakamwa kwa amayi apakati pamlingo wa 30-100 mg kuti akope ntchito.
Pogwiritsidwa ntchito kukonza magwiridwe antchito, a Dinoprost tromethamine Nthawi zambiri amaperekedwa ndi jakisoni wamitsempha, wodziwika bwino chifukwa chokhoza kupanga kukula kwakanthawi.
Malo opangira jakisoni amaphatikizira mapewa, ma biceps, ma triceps, ana amphongo, chifuwa, kumbuyo ndi miyendo. Wogwiritsa ntchito amangobaya minofu imodzi patsiku koyambira kwamankhwala, koma izi zitha kukulitsidwa mpaka jakisoni 2 kapena kupitilira apo patsiku chifukwa azolowera mankhwalawo ndi zotulukapo zake.
Gwiritsani ntchito kumayamba pang'onopang'ono ndikuyamba ndi muyeso wotsika wa pafupifupi mamiligalamu 0,5 pa jakisoni.
Ngati jakisoni woyamba adalandira popanda zovuta zina, jakisoni wotsatira ayenera kukulitsidwa mpaka 1 milligram (mg), ndiye kuti, adzawonjezeka pang'onopang'ono ndi 0,5 mg pakufunsira mpaka kuchuluka kwake kukufika, komwe kumatha kukhala 5 mg pa malo obayira jekeseni.
Malo obayira jekeseni nawonso amayendetsedwa pafupipafupi kotero kuti masiku angapo amalekanitsa makonzedwe mgulu limodzi la minofu.
Dziwani kuti kwa ena, kupweteka pambuyo pa jakisoni kumakhala kovuta kwambiri kotero kuti kuphunzitsidwa kwa gulu lamtunduwu kuyenera kuchedwa kwa masiku ochepa.
Kumvetsetsa kwamunthu payekhapayekha kungafune kusinthidwa kwa jekeseni wanu ndi dongosolo la maphunziro kuti mukulitse zotsatira ndi chitonthozo.
Komabe,
Monga inu anabolic steroidskapena Dinoprost tromethamine ndi mankhwala omwe adapangidwa ndi cholinga china osati ndi magwiridwe antchito / phindu pakupanga zolimbitsa thupi. Komabe, popeza chilichonse chimagwiritsidwa ntchito ndi akatswiri azamasewera (mosasamala za thanzi kapena ayi) kenako ndikuyamba kugwiritsidwa ntchito ndi akatswiri, zomwezo zidachitika ndi dinoprost.
Zili ndi inu kudziwa zomwe mukufuna kuchita ndi thupi lanu, kuwunika zoyipa zake ndikuzindikira ngati zili zoyenera kugwiritsa ntchito kapena ayi.
Za Post Author
Momwe mungagwiritsire ntchito kupatsa padera miyezi isanu ndi umodzi
Sitimathandizira pakugwiritsa ntchito izi. Pazifukwa izi, pitani kuchipatala.
Moni!
adakonda nkhaniyo.
Koma ine ndikufuna kudziwa ngati ine ndingagwiritse ntchito dinoprost ambiri osati localized.
Ndili ndi mbolo yowonongeka kwambiri komanso yaying'ono, nditha kugwiritsa ntchito Lutalyse, pa mbolo yanga, ndi mlingo wa 0,3 ml, kuti ndikule ndi kukhazikika.
Jekeseni kachinthu kakang'ono kameneka mutiuze chomwe chinali kkkkkkkkkk
angagwiritsidwe ntchito mwachindunji pa mbolo, ndi mlingo wa 0,3 ml
Ndi syrinji iti yoti mugwiritse ntchito ngati munthu aigwiritsa ntchito?